The World’s Leading AF4 Contract Lab

SOLVE is a contract analytical lab, located in Sweden and the US, operating highly specialized instrumentation to help you gain knowledge about your materials. We are a qualified team of PhD level scientists and we provide the best analytical capabilities in our quality controlled lab as well as customized consultation services.

Field-flow fractionation – one of our core technologies

One of our core technologies – field-flow fractionation, AF4 – is a recommended method for small nanoparticles up to large polymers as well as fragile protein aggregates, and can be applied standalone or orthogonal to our other techniques.

Contact us today, we are excited to work with you.

Our most requested techniques

The materials that we focus on


Ex vivo biologics characterization

Using our core characterization method AF4, we probe protein therapeutic characteristics and behavior in plasma, serum and whole blood – thus providing a route to investigate parenteral drugs in its intended in vivo application in an effort to improve patient cohort selection. This in order to maximize the positive impact of the drug while mitigating…

Improved characterization of complex charged molecules

SOLVE can now offer enhanced separation and characterization of complex charged molecules, invaluable for exosomes, drug delivery vehicles, colloidal stability of proteins etc. We have included Wyatt’s new system EAF4 Mobility, that combines electrical and flow fractionation in a single separation, to our instrument park. This is the most versatile separation technology available, with the…