Sunscreen nanoparticles

One of the most frequent questions we get at SOLVE is if we can characterize and quantitate nanoparticles in food and cosmetic products. ”Of course we can” said our scientists, ”let’s show them!” Many consumer products contain nanoparticles – diameter 1-100 nanometers (one nanometer is 0.000001 millimeter). The most known product is probably sunsceen, where…

Helping nano-entities discover their nano-identity

Having a polydisperse nanomaterial? Nanoparticles are often characterized by techniques such as dynamic light scattering (DLS) and/or imaging methods such as transmission electron microscopy (TEM) and scanning electron microscope (SEM). The suitability of these methods to measure polydisperse samples is sometimes questioned because they have considerable draw backs such as extreme bias towards small numbers…

A spoon full of levan…

At SOLVE we have developed a robust, reliable, fast and green method (no harmful chemicals or by products are generated) to accurately characterize levan with respect to molar mass and size distributions using asymmetric flow field-flow fraction coupled with online multiangle light scattering and differential refractive index (AF4-MALS/dRI) detection. Successful characterization of raw levans with…

Protein purification is more than monkey business

One client of ours – a small biotech company with five employees – was experiencing extremely low yields of their recombinant protein during purification. Upwards of 25–30 repetitive purification steps were needed to collect enough mass of the desired product. They were unable to diagnose the origin of problem through the use of traditional protein…