Formulation of drug products is important to obtain stable, tolerable and safe pharmaceutical products. SOLVE work with formulation during all stages of the development process, both early discovery, during process optimization and later stage quality control before toxicological and clinical testing.
Much of SOLVEs work in the field of formulation is focused on analysis and characterization for the purpose of determining aggregation, degradation, and interactions. We work with a variety of sample types, from peptides, proteins, antibodies, to viruses, nanoparticles and other carriers of an API. We have also extensive experience of analyzing and characterizing excipients.
Depending on the development stage, number of samples, requirement of the analysis and question at hand different techniques may be the most appropriate. At SOLVE we specialize in particular on the use of techniques such as DLS, SEC-MALS AF4-MALS and AUC. We also offer a wider range of other complimentary techniques, either in-house or through cooperation with partnering companies.