Analysis of aggregates of therapeutic proteins is crucial to ensure patient safety

Our article is out! The analysis of aggregates of therapeutic proteins is typically performed in the finished formulation to ensure that aggregates are not present. An important question is, however, what happens to therapeutic proteins, with regard to oligomerization and aggregation, after they have been administrated (i.e., in the blood)? Read about our size characterization of proteins and antibodies in serum, plasma, and whole blood using AF4.

https://doi.org/10.1007/s00216-018-1127-2